HP previewed their new tablet PC at the 2010 Consumer Electronics Show. Apple will release their version later this spring. Sounds to me like this could supplant the Kindle, Nook and other e-Reader devices. It might also be the impetus for EPUB distribution. e-Readers are nice, but they're one trick ponies.
From an education publishing perspective, this could really open the door to new revenue models for schools at all levels to distribute published content. It also opens the door for new models for authors writing content.
More on these ideas later.